What's New

Brendel group in the Indiana Daily Student news (Dec. 12, 2016)

Volker Brendel elected AAAS Fellow (Oct. 2016); IU News Release (Nov. 21, 2016)

Check out our github site!

Raborn, R.T., Spitze, K., Brendel, V.P. & Lynch, M. (2016) Promoter architecture and sex-specific gene expression in Daphnia pulex. Genetics 204, 593-612. [online article]

Duvick, J., Standage, D.S., Merchant, N. & Brendel, V.P. (2016) xGDBvm: A Web GUI-driven workflow for annotating eukaryotic genomes in the cloud. The Plant Cell 28, 840-854. [online article]

Standage, D.S., Berens, A.J., Glastad, K.M., Severin, A.J., Brendel, V.P. & Toth, A.L. (2016) Genome, transcriptom and methylome sequencing of a primitively eusocial wasp reveal a greatly reduced DNA methylation system in a social insect. Molecular Ecology 25, 1769-1784. [online article]


The Brendel Group provides domain expertise to advise the Jetstream national science and engineering cloud project.

V. Brendel serves on the CyVerse External Advisory Board.

V. Brendel serves as Consulting Editor of The Plant Cell.

PlantGDB News:

xGDBvm on YouTube



Description: The PairwiseStatSig program estimates the pairwise statistical significance of a pairwise local alignment of two protein sequences independent of any database using censored Maximum Likelihood Fitting.

Citation: Agrawal, A., Brendel, V. & Huang, X. (2008) Pairwise statistical significance versus database statistical significance for local alignment of protein sequences. In I.I. Măndoiu, R. Sunderraman & A.Z. Zelikovsky (eds.), 2008 International Symposium on Bioinformatics Research and Applications, May 6-9, 2008, Georgia State University, Atlanta GA, U.S.A.. Lecture Notes in Bioinformatics 4983, 50-61. [online abstract]; Agrawal, A., Brendel, V. & Huang, X. (2008) Pairwise statistical signifiance and empirical determination of effective gap opening penalties for protein local sequence alignment. Int. J. of Computational Biol. and Drug Design, 1(4), 347-367; to appear.

Download: Download PairwiseStatSig