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BIOL Z620 Spring 2013

Selected Topics in Zoology (Section 28329):
Introduction to Bioinformatics and Genomics

BIOL Z620 Spring 2013


Course description

BIOL Z620 ItBG

Lecture times and locations

Mon, Wed 12:45p-2:15p, Lindley Hall (LH) 030

Tentative schedule (click the icon for a PrinterFriendly.gif version)

DAYDATELECTURETOPICLECTURER
Mon Jan 7 1.1 Orientation
Introduction to informatics and computation in biology
Volker Brendel
Wed Jan 9 1.2 Introduction to genomic approaches in biology
The CTFR gene as a case study
Irene Newton
Mon Jan 14 2.1 Perl for bioinformatics scripting:
Introduction (Learning Perl, Chapter 1)
Scalar Data (Learning Perl, Chapter 2)
Scripting assignment 1
Irene Newton
Wed Jan 16 2.2 Perl for bioinformatics scripting:
Lists and Arrays (Learning Perl, Chapter 3)
Hashes (Learning Perl, Chapter 5)
Scripting assignment 2
Irene Newton
Mon Jan 21 MLK Jr. Day - no class n/a
Wed Jan 23 2.3 Perl for bioinformatics scripting:
Subroutines (Learning Perl, Chapter 4)
Scripting assignment 3
Irene Newton
Mon Jan 28 2.4 Perl for bioinformatics scripting:
I/O Basics (Learning Perl, Chapter 6)
Filehandles and File Tests (Learning Perl, Chapter 11)
Scripting assignment 4
Irene Newton
Wed Jan 30 2.5 Perl for bioinformatics scripting:
Regular Expressions (Learning Perl, Chapters 7-9)
Scripting assignment 5
Irene Newton
Mon Feb 4 3.1 Sequence alignment
Reading assignment 1
Volker Brendel
Wed Feb 6 3.2 Sequence alignment
Volker Brendel
Mon Feb 11 4.1 Sequence alignment
Volker Brendel
Wed Feb 13 4.2 Sequence alignment
Volker Brendel
Mon Feb 18 4.3 Sequence alignment
Irene Newton
Wed Feb 20 4.4 Sequence alignment
Volker Brendel
Mon Feb 25 5.1 Molecular Phylogeny:
Reading assignment 3
Volker Brendel
Wed Feb 27 5.2 Molecular Phylogeny:
Parsimony and Distance Matrix Methods
Volker Brendel
Mon Mar 4 5.3 Molecular Phylogeny:
Project-related computational laboratory
A list of Web-servers for molecular phylogeny analyses
Mobyle @ Pasteur
Data analysis assignment 2
Volker Brendel
Wed Mar 6 5.4 Genome assembly and annotation:
Project-related computational laboratory
Data analysis assignment 3
Instructors
Mon Mar 11 SPRING BREAK - no class n/a
Wed Mar 13 SPRING BREAK - no class n/a
Mon Mar 18 6.1 Gene expression analyses:
Reading assignment 6
Irene Newton
Wed Mar 20 6.2 Gene expression analyses:
Irene Newton
Mon Mar 25 6.3 Gene expression analyses:
Project-related computational laboratory
Data analysis assignment 3
Instructors
Wed Mar 27 7.1 Protein structure:
Secondary Structures (Understanding Bioinformatics, Chapter 5)
Reading assignment 7: Review of Protein Structure Prediction
Resources: A listing of protein structure prediction servers
Volker Brendel
Mon April 1 7.2 Examples of Perl usage for protein structure data:
Parsing PDB files
Processing of program output
(Requires STRIDE, available via ftp)
Volker Brendel
Wed April 3 7.3 Protein structure:
Project-related computational laboratory
Data analysis assignment 4
Instructors
Mon April 8 8.1 Back to Perl I: Putting bits and pieces together for protein secondary structure analyses Volker Brendel
Wed April 10 8.2 Back to Perl II: Using BioPerl Volker Brendel
Mon April 15 8.3 Special topics - Metabolic reconstruction
Reading assignment 9
Irene Newton
Wed April 17 8.4 Special topics - Metabolic reconstruction:
Project-related computational laboratory
Data analysis assignment 6
Instructors
Mon April 22 9.1 Final project preparation Instructors
Wed April 24 9.2 Final project preparation Instructors
Wed May 1 11:59pm Final Projects due students