What's New

Raborn, R.T., Spitze, K., Brendel, V.P. & Lynch, M. (2016) Promoter architecture and sex-specific gene expression in Daphnia pulex. Genetics [Early online: 31 August 2016]

Duvick, J., Standage, D.S., Merchant, N. & Brendel, V.P. (2016) xGDBvm: A Web GUI-driven workflow for annotating eukaryotic genomes in the cloud. The Plant Cell 28, 840-854. [online article]

Standage, D.S., Berens, A.J., Glastad, K.M., Severin, A.J., Brendel, V.P. & Toth, A.L. (2016) Genome, transcriptom and methylome sequencing of a primitively eusocial wasp reveal a greatly reduced DNA methylaiton system in a social insect. Molecular Ecology 25, 1769-1784. [online article]


The Brendel Group provides domain expertise to advise the Jetstream national science and engineering cloud project.

V. Brendel serves on the CyVerse External Advisory Board.

V. Brendel serves as Consulting Editor of The Plant Cell.

PlantGDB News:

xGDBvm on YouTube



Description: SAPS stands for Statistical Analysis of Protein Sequences, and SSPA is an acronym for Significant Segment Pair Alignment. These programs are rather old (see citations), but still in use. I am making the old code available as is for now, hoping for some time soon to update the code. In the meantime, give me feedback and suggestions! Volker Brendel, December 16, 2008.

Citations: SAPS - Brendel, V., Bucher, P., Nourbakhsh, I.R., Blaisdell, B.E. & Karlin, S. (1992) Methods and algorithms for statistical analysis of protein sequences. Proc. Natl. Acad. Sci. USA 89, 2002-2006. [PubMed ID: 1549558] [PDF]; SSPA - Karlin, S., Weinstock, G. & Brendel, V. (1995) Bacterial classifications derived from RecA protein sequence comparisons. J. Bacteriol. 177, 6881-6893. [PubMed ID: 7592482]

Web Implementations: SAPS @ EBI; SAPS @ Mobyle

Download: Download SAPS-SSPA