What's New
Recent papers:
Daniel S Standage, Tim Lai & Volker P Brendel (2022)
iLoci: Robust evaluation of genome content and organization for provisional and mature genome assemblies.
Nucleic Acids Research Genomics and Bioinformatics
4, Issue 1, March 2022, lqac013, https://doi.org/10.1093/nargab/lqac013
[PubMed ID: 35211671]
[online article]
[PDF]
Morandin, C., Brendel, V.P., Sundström, L.; Helanterä, H. & Mikheyev, A. (2019)
Changes in gene DNA methylation and expression networks accompany caste specialization and age-related physiological changes in a social insect methylation.
Molecular Ecology,
28, 1975-1993.
[PubMed ID: 30809873]
[online article]
[PDF]
The future of computational genomics:
Brendel, V.P. (2018)
From small RNA discoveries to a new paradigm in computational genomics?
New Phytol.
220, 659-660.
[PubMed ID: 30324739]
[online article]
[PDF]
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PairwiseStatSig
Description: The PairwiseStatSig program estimates the pairwise statistical significance of a pairwise local alignment of two protein sequences independent of any database using censored Maximum Likelihood Fitting.
Citation: Agrawal, A., Brendel, V. & Huang, X. (2008)
Pairwise statistical significance versus database statistical significance for local alignment of protein sequences. In I.I. Măndoiu, R. Sunderraman & A.Z. Zelikovsky (eds.),
2008 International Symposium on Bioinformatics Research and Applications, May 6-9, 2008, Georgia State University, Atlanta GA, U.S.A..
Lecture Notes in Bioinformatics 4983, 50-61. [
online abstract]; Agrawal, A., Brendel, V. & Huang, X. (2008)
Pairwise statistical signifiance and empirical determination of effective gap opening penalties for protein local sequence alignment. Int. J. of Computational Biol. and Drug Design,
1(4), 347-367; to appear.
Download:
Download PairwiseStatSig